As the hugr rice in diseases is obeserved in this modern populated genration where people couldnot able to take care of their health.A question always goes in theit mind of buying which medicines which is cheap and best in theit budget.
Well, since a long span of time generic drugs being a part of society were not as much popular as the ethical drugs.Along with this people were not aware of the drugs that they are medicated.However,giving them branded drugs was convient to them as much populatoion was not literate as they should.But now this has being increasing day by day as society is giving their awareness towards they medication they are taking also the action and work of drugs with their composition.
Hence,generic drugs is taking a huge place similar to branded medicines.Also as community is giving their presence towards it resulting in rise in demand of it.Moreover, the other benefit which mankind find from generic medication is the huge wage cut down.This is the major reason people turning towards the generic.
Well but still few population being aware of it completely does not initiated to take generic medicines, as they have fear that being low cost it must be not as good as the branded medications. Patients suffering from disease like heart attack and diabetes have a fear that in taking such medicines may cause some internal damage to their body.However, living with this mindset is completely wrong.
Though their is increasing demand of generic drugs due to sudden awareness but few questions which runs during buying such drugs remains the same.But people should know that using generic drugs instead of ethical branded drugs is not harmful as they think.On the controtary it also depends on the individual’s body that how the drug give response.Also many generic drugs have just different brand name but manufacturing unit are same as ethical drugs.
Further, another question which comes in people mind is why it has a such huge price difference.Which can be elaborated as the compound and composition taken for production of tablets, capsules and syrup are one only.Also every medicines which comes in market and the one which gets punctuated are first tested by government agency where the test performed are same for both ethical and generic with same procedure and test results get passed by authorized officers then the batch is allowed to continue it’s production.If in circumstances the one of the test gets failed and manufacturing unit could not able to resolve it then it may happen that the compounds and the batch components can be destroy.
Well, this can be elaborated by taking one of the popular pain killer an NSAIDS drugs known as paracetamol.however, obeserving the composition and contents of calpol 500 which is the ethical form of paracetamol contains paracetamol 500mg which is manufactured by Galaxosmithkline Pharmaceuticals Ltd consisting price of 14.7/strip of 15 tablets .Whereas, the generic form of analgesic drugs known as paracip 500 which is manufactured by Cipla Ltd consisting price of 9.40/strip of 10 tablets.Hence, its just the change and difference of manufacturing units and not other aspects.Concluding Society can take generic as well ethical medicines with no fear.
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In this Contemporary Era, where society consuming fast food and street food in a huge quantity consequently increasing demand where people are unaware whether is it healthy or not for them. Are they aware of the ingredients used for its preparation? However, this has increased due to insufficient time during their working hours resulting in they find such eatable’s in a convenient way. Also, is it easily available from online apps and home delivery or restaurants and cafes near them. So, I will discuss about this in this article whether they are safe or not.
Nowadays, the junk food is in huge demand and adapted by every single age rapidly. Also, in this modern system young pupils and working people had to travel a long distance for reaching at their work place which doesn’t give sufficient time time to cook food themselves. On the contrary, people find it easy to handle and carry and consume it. Moreover, they also get tired from their hectic schedule whether it’s a child or teens or young working parents.
WHAT IS JUNK FOOD!!!!!
Junk food is high calorie food which lacks in minerals, vitamins, and other essential nutrients which are required for daily metabolism of human but contain high energy an fiber which Detroy the body system having unconditional food value which just fulfills mankind desire but do not help for better growth of human.
WHAT ARE THE COMPONENTS OF JUNK FOOD!!!!!
This high calorie processed food contains high levels of refined sugar, white flour, trans saturated and poly saturated fat, salt and additives such as monosodium glutamate and tartrazine, food colour’s and enhance flavor for their attractive texture and increased shelf life. This calorie rich harmful food containing fats are a complex structure of elaidic acid (junk food and bakery products) and vaccinic acid (dairy products).
Studied have proved that elaidic acid have increased glucose- stimulation insulin secretion along with the inhibition of oxidation of glucose.However, this mechanism distrubes the glucose metabolism, damages beta cells by eventually leading to TYPE 2 Diabetes mellitus. Moreover,elaidic acid had a toxic effect on human EndoC-betaH1 beta cells though many studies did not support this.
HOW TO IDENTIFY JUNK FOOD!!!!!
Their are many attractive packed products which catches human eye due to the label and pictures.This eye catching high calorie processed food contains:-
>35% of calories from fat
>10% of calories from satuarated fats
Tran fat
>35% of calories from sugar, unless it is made of no added sugar.
>200 calories per servings
>200 mg sodium salt per serving.
HOW METABOLICLY IT PLAYS HARMFUL ROLE IN HUMAN BODY!!!!!
When food is oxidized in body it cause enormous formation of acetyl CoA characterizing it out into mitochondria for its participation in metabolic pathway and for its effective utilization.These pathway include denovo fatty acids synthesis and biosynthesis of cholesterol causing formation of excess cholesterol in body. Another pathway is formation of ketone bodies which get active during impaired glucose tolerance sets in. Addition to this, when refined sugar is consumed, the pancreatic secretes high amounts of insulin to prevent a dangerous spike in blood sugar levels.lastly, a high sodium level has been clearly implicated causative factor for high blood pressure.
Hence, say no to JUNK FOOD from today and yes to HEALTHY FOOD………
Since ancient times Ayurveda has played an essential role in treatment of disease as well as maintaining their healthy life by consuming natural herbs which are obtained from natural resources.Although ancient vedic were having many rapid and herbal solutions which they have also proposed in different smahitas with their detail remedies also they used to determine disease by pulse and tongue method which also gave them accurate prediction which they used to cured by their natural remedies where they got expertise in passing years. Moreover, ancient civilization followed this technique as it was not harmful and free from any side effect.
As,nowadays major society suffering from short term memory loss or long term memory loss.Also,many school going teens fails in memory boosting due to insufficient vitamins and minerals which are not consumed by them in their daily diet.This is observed in world throughout by different age group where many people consumes smoking,alcohol, drugs and unable to follow healthy diet due to busy lifestyle which do not give sufficient time to maintain their health.Also many research are also carried in universe by experts.However, they fails for accurate results for many medicinal products which are pursued as a memory enhancer.
WHICH PLANTS PARTS ARE USED AS A BRAIN BOOSTER
In pharmacology their are many natural herbs and their parts which are mentioned as a brain enhancer drugs.However,studied by scientist it is said that very few natural elements have proved and given 99% of the result.
Some of the plants which are used for increasing memory are bacopa monnieri, cumin,peppermint, ginkgo bilobo, rosemary oil, shankh pushpi and mandukaparni, ashwagandha.
This plants have different chemical composition which helps as a brain stimulation also it increase blood circulation as well as nerve impulse transmission.With the increase in blood circulation they also have other vitamins and minerals which forms the sheath and covering of the nerve as it make them strong for long term memory. This drugs have different parts which have different constituents where studies are carried out using it.
HOW DOES THE MEMORY ENHANCER DRUGS WORKS AS BRAIN STIMULATION
1.GENE EXPRESSION :-
One of the first mechanisms identified as critical for long-term memory consolidation is the requirement for de novo protein and RNA synthesis. Similar requirements have been found for long-term plasticity, including long-term facilitation in Aplysia californica and a phase of LTP that lasts more than one hour, known as late-LTP. Regardless, the findings that in addition to pharmacological approaches molecular and genetic methods have provided evidence that transcription and translation are essential for memory. from growth factor stimulation of tyrosine kinase receptors coupled to the activation of Ras and extracellular signal-regulated kinase (ERK); to G-Protein Coupled Receptor (GPCR) activation coupled to activation of adenylyl cyclase, increase in cAMP, and activation of protein kinase A (PKA); to the activation of stress pathways and glutamate release leading to release of intracellular calcium and relative downstream events. All of these pathways can lead to the activation of an activator form of CREB, CREB1. This activation in turn can lead to the transcriptional regulation of a number of target genes, including immediate early genes.
2.SYNAPTIC MODELING:–
Long-term memory formation is critically associated with synaptic remodeling, including the growth or pruning of synapses, as well as altered synaptic efficacy. These changes occur through a number of local regulations, including mRNA translation, protein degradation, remodeling of cytoskeleton, and receptor trafficking into and out of the synapse.One of the first transgenic manipulations that produced memory enhancement targeted receptor trafficking .NR2B subunit was overexpressed in prefrontal cortex, working memory tasks such as the T-maze and a modified water maze were also enhanced.Pharmacological studies indicated that manipulations of NMDA receptors (NMDARs) can enhance both working memory and LTM-consolidation suggesting that synaptic glutamate receptor expression and trafficking play a significant role in enhancing memory formation and maintenance. Enhancement via NMDARs can be obtained both with agonists and low doses of antagonists, suggesting that a tight regulation of NMDARs is required in order to facilitate memory processes.The memory enhancement effects after increasing NR2B that they may occur in part by the facilitation of LTP in these regions, whereas overexpression of an alternate subunit, NR2A, facilitates LTD, perhaps because NR2B containing NMDARs are more calcium permeable than NR2A-containing NMDARs.The ability for NR2B overexpression to result in memory enhancement may occur through the subsequent increased ability of NMDA receptors to be activated due to their increased number. Another critical receptor type that has been implicated in memory enhancement is the 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid (AMPA) receptor. Though, like NMDARs, AMPARs respond to glutamate, they do not have a magnesium block and are therefore activated with less depolarization of the cell.
3.NEUROMODULATION:–
Neuromodulators, which alter cellular and synaptic properties via widespread projections have a well-known role in memory function and many modulation pathways have been targeted for memory enhancement. In contrast with many other diseases of cognitive impairment, PD is specifically accompanied by deficits in tasks associated with prefrontal cortex, including executive function and planning, rather than with memory consolidation impairments. Dopamine is thus widely thought to be extremely important for working memory tasks relying on the prefrontal cortex (PFC), and low levels of dopamine receptor D1 (DRD1 or D1) antagonists enhance working memory as revealed by an increase in neuronal activity during a delay period of a delayed-non-match-to-sample task, whereas high levels of antagonists and agonists both impair that activity.
In addition to pharmacological approaches, there are a number of behavioral manipulations that have been found to be effective in promoting memory enhancement. First, repetition has long been known to enhance memory performance, and it has been consistently shown that repeated training or learning events are associated with better memory.Similarly, memory can be enhanced by targeting retrieval-induced reconsolidation, which occurs through repeated retrieval sessions.
studied has proved that consuming naturals herbs such as brahmi , ashwagandha, bacopa monnieiri for up to 40 days can initiate stimulation of memories boosting by giving a tremendous results for long term memories.
Reasons why a drastic low level of heamoglobin obeserved in humans!
Nowadays,due to busy lifestyle of society many people couldnot able to manage their healthy life.However,due to insufficient pace of time individual fails for regular intake of healthy foods.Consecuently,this leads in increase of diseases and many times also fails as a death.
WHAT INDIVIDUAL FACES DUE TO LOW HEMOGLOBIN !
As the recent test resulted that due to decreased level of Hb in blood many mankind suffers from anameia, low strength to work, unconsciousness,weakness,shortness of breadth and many more as the need of protein becomes highest among the man.However, instead of taking essential supplements they could not able to control the minimum level of hemoglobin.Although, the minerals and vitamins such as vitamin B complex, calcium,vitamin D3, and other pivotal minerals required for human healthy growth are lacking in a vegetables and friuts whcich are availaible in market.However,the of harmful chemicals destroy human body also.
Many times being unaware of disease they have a heart attack which causes death due to supply of insufficient oxygen.Also awareness for this is not much being enclosed where people fails to help ther patient during severe condition.
WHAT CAN BE DONE TO OVERCOME THIS !
As technology is increasing rapidly and new drugs are scientifically tested and invented daily.Many medicines are available in the market for increasing level of hemoglobin also they range from different prices depending upon the manufacturing unit.Though being eating natural food and vegetables are much better good for health also blood circulation will rise naturally.
Some fruits such as pomegranate,apple,kevi and few nuts such as walnuts and fig are the 1st prescribed by people.Also iron rich green leafy vegetables such as spinach, beetroot, tofu, asparagus, chicken liver, whole egg, oysters should be taken to increase hemoglobin level in blood where the RBC’s cells will also not get ruptured giving a human a healthy life.
Also, the vegetables and fruits brought from the market can be made sulphur free with washing it with oxygenated solutions which destroy death giving micro-organisms.Hence, precaution can be give a wealthy and healthy life.
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